For many intensive care units TGC/IIT causes significant cost and resource problems and maintaining a patient's glucose level within a tight target range is difficult using current clinical practice. As a result, glucose monitoring is often performed at a frequency that significantly reduces patient care benefits while increasing the risk of hypoglycaemia. Multiple studies over the past few years have shown an association between even one mild hypoglycemic event and increased mortality.
To date, the single greatest barrier to adopting TGC/IIT is the absence of an appropriate technology on the market to meet the need for tight control, ease of use, and automated monitoring.
See Clinical demand to read what the experts say.
Kosiborod et al, Circulation.
U-shaped mortality curve showing increased risk of mortality at both hyper and hypoglycemic levels. Fear of increasing hypoglycemia due to the limitations of current intermittent technology has resulted in a majority of clinicians opting for looser or higher target ranges.